Ipamorelin 5mg
In laboratory and endocrine research settings, Ipamorelin has been investigated in relation to:
- Growth hormone (GH) release and pulsatility
- Ghrelin receptor (GHSR-1a) signaling pathways
- GH-IGF-1 axis regulation
- Bone and connective tissue research
- Endocrine signaling selectivity and specificity
- Pharmacokinetic and pharmacodynamic modeling of GH secretagogues
$ 72.00
Out of stock
- For Research Use Only. Not for human or veterinary use. Not intended for medical, diagnostic, or therapeutic applications.
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Peptides are not ready to use. Must purchase BAC water for reconstitution.
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Ipamorelin is a synthetic pentapeptide growth hormone secretagogue designed to selectively activate the ghrelin (GHSR-1a) receptor. It is commonly investigated for its ability to stimulate growth hormone release while minimizing activation of other pituitary hormones. Researchers utilize Ipamorelin in laboratory studies examining GH signaling dynamics, endocrine selectivity, and skeletal and metabolic pathways influenced by growth hormone activity.
Research suggests Ipamorelin is involved in several key biological processes related to growth hormone signaling:
Selective Growth Hormone Release
Ipamorelin binds to the ghrelin (GHSR-1a) receptor on pituitary cells, triggering growth hormone release while showing minimal stimulation of stress-related or reproductive hormones. This selectivity makes it useful for studying GH-specific effects without broad endocrine disruption.
Natural Growth Hormone Pulses
Ipamorelin stimulates growth hormone release in short, rhythmic pulses rather than continuous exposure. This allows researchers to study GH patterns that more closely resemble natural endocrine signaling.
GH–IGF-1 Signaling
By increasing endogenous growth hormone output, Ipamorelin indirectly influences IGF-1 signaling, supporting research into tissue maintenance, metabolism, and skeletal biology.
Bone & Connective Tissue Research
Experimental studies have associated Ipamorelin-induced GH release with changes in bone growth, bone mineral content, and connective tissue activity, making it relevant in skeletal and structural research contexts.
Endocrine Signaling Specificity
Because Ipamorelin was designed to avoid significant activation of ACTH and cortisol pathways, it is frequently used to explore clean GH-axis signaling without confounding stress-hormone effects.
Elite Bioscience supplies Ipamorelin strictly for laboratory, analytical, and in-vitro research.
This study demonstrated dose-dependent increases in bone growth alongside robust GH release, without significant stimulation of prolactin or ACTH.
Read StudyThis landmark paper established Ipamorelin’s receptor selectivity, showing strong GH pulses with minimal off-target endocrine activation.
Read StudyIpamorelin significantly increased bone mineral content and markers of bone formation, supporting its relevance in skeletal research.
Read StudyThis study showed restoration of bone-forming activity and GH secretion in models of stress-induced bone loss.
Read StudyMechanistic work demonstrating how ghrelin-family peptides activate intracellular signaling pathways linked to GH release and cellular response regulation.
Read StudyChemistry
Supplier: Elite Bioscience®
Product Form: 1 × 5 mg sterile, lyophilized peptide vial
Active Ingredient: Ipamorelin (NNC 26-0161)
Chemical Name: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Molecular Formula: C₃₈H₄₉N₉O₅
Peptide Class: Selective growth hormone secretagogue (GHS); ghrelin receptor (GHSR-1a) agonist
Research Use: For laboratory, in-vitro, and analytical research only. Not for human or veterinary use.
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